Reviewed and Updated: August 22nd, 2024

Reishi mushrooms; what makes them so special out of thousands of mushrooms out there? Well, beyond its place at the dinner table, reishi mushrooms have been used as a health remedy for centuries spanning immunity, mood, and even heart health. So let’s take a closer look at the potential benefits of these mushrooms and see if they’re right for you. 

The Benefits of Reishi Mushrooms

Immune Support

Reishi mushrooms contain several compounds that may provide immune-supporting benefits including antioxidants, beta-glucans (a polymer of β-D-glucose), and triterpenes. In this 2021 review, beta-glucans were cited as having an immunomodulatory effect against COVID-19. 

Furthermore, test-tube studies show that reishi may promote white blood cell production, the primary cells of the immune system: which can improve the fight against infection and cancer cells.

Could Reduce Fatigue

It’s difficult to measure fatigue since there aren’t specific biomarkers, but study participants often report decreased levels after trying reishi. The exact cause of chronic fatigue isn't well understood. But experts theorize that there are several sources such as infections, immune problems, stress or hormonal imbalances. 

Reishi’s fatigue-fighting benefits may come down to the previously mentioned immune boosting and antioxidant activities that suppress free radical/oxidative damage. Reishi mushrooms may also help to support healthy testosterone levels which further contribute to healthy energy levels as well as anxiety and depression. 

Might Reduce Blood Pressure

In animal studies, reishi has been shown to reduce blood pressure at similar levels to certain medications. Interestingly, reishi may be unique in that it stimulates blood flow in the brain to the extent that it may provide some nootropic (brain-boosting) properties. 

For this reason, it’s important to consult your physician if you want to take Reishi especially if you’re on blood-thinning or hypertension medications since taking them together can drop blood pressure too low which is not recommended.  

Could Help with Brain Aging

Reishi mushrooms have been studied for Alzheimer’s disease and throughout those studies, the triperpenoids in Reishi were found to be neuroprotective because they inhibit the degradation of neurotransmitters. 

In everyday terms, Reishi may provide a path to healthy brain aging and prevent aspects of neurodegenerative problems due to its antioxidant and antiinflammatory properties. Reishi mushrooms may prevent progression of Alzheimer’s and Parkinson’s since both diseases are a result of oxidative stress and inflammation. 

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May Provide Calming Properties

Reishi mushrooms might also help provide a bit of calm as one animal study demonstrated that polysaccharides from Reishi conferred anti-depressant and anti-anxiety benefits in rats. These mushrooms are trusted to provide calm and alleviate stress since they interact with the GABA receptors in the brain in a way that can induce relaxation.

But in a different limited study results were more mixed. 

Blood Sugar

Sugar and its effects on health are widely discussed right now and reishi has been looked at in this context but as with other areas, data is limited by a lack of human trials. In mice, Reishi indicated hypoglycemic activity by increasing plasma insulin levels and decreasing plasma sugar levels. This is accomplished by stimulation of calcium ions into the beta pancreatic cells which secrete insulin to break down glucose. Also, following a healthy diet low in carbohydrates and refined sugars will help further decrease blood sugar since the pancreas will have less glucose to break down.

Antioxidant Status

Many conditions of aging come down to oxidative damage and the way it wears the body down. Its components act as scavengers looking out for free radicals and eliminating them. As you may have heard Antioxidants are the main (natural) way to offset this damage and multiple tests have shown that extracts from Reishi’s fruiting bodies provide powerful antioxidant benefits. 

Drug Interactions

Medline Plus advises caution for people who take blood pressure, blood thinning, and diabetes medications. 

Who Should Not Take Reishi?

People with allergies to mushrooms or fungal products should absolutely not take Reishi. 

Additionally, those who are pregnant or breastfeeding, people preparing for surgery, and people with bleeding disorders should avoid reishi mushrooms due to potential adverse effects on hormones and blood clotting.

Also, consult with your doctor or pharmacist if you take blood pressure medication, diabetes medication, and blood thinners before taking supplements of Reishi mushrooms since they can increase the effects of these medications.

Interested in Getting the Benefits of Reishi? 

Best Rei-Shi Plus from Best in Nature. The convenient capsules provide potent extracts from these specialized mushroom strains. All of which are produced from live mycelial and fruiting stages of fungi grown on organic brown rice under controlled, hygienic, chemical-free and yeast-free conditions. Then, the Reishi mushrooms are harvested at the peak of their vigor.

Bottom Line

Reishi could have a number of benefits on immunity, energy levels, mood health, and blood sugar. In some areas, study respondents have reported positively on Reishi supplementation. If you’re interested in its benefits, talk to your physician to see if it could be right for you. 

This article is provided for informational purposes only and is not intended to be used as medical advice. If you have immediate concerns about your health, please seek the help of your physician.